KMID : 0614620100560040236
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Korean Journal of Gastroenterology 2010 Volume.56 No. 4 p.236 ~ p.241
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Rates of Early Surgery and Associated Risk Factors in Crohn¡¯s Disease
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Jeon Su-Jin
Lee Kwang-Jae Lee Myung-Hee Lim Sun-Gyo Kang Chang-Jun Kim Jin-Hong
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Abstract
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Background/Aims: The individual course of Crohn¡¯s disease is diverse, and some patients may require bowel resection. The aims of this study were to determine the early surgery rate of Crohn¡¯s disease and to identify risk factors associated with early surgery in Korea.
Methods: Ninety six patients with Crohn¡¯s disease (68 men; median age at the time of diagnosis: 25 years), who had been followed up more than a year, were retrospectively analyzed. Early surgery was defined as a bowel operation for Crohn¡¯s disease or its complications occurring within 3 years from diagnosis. Early surgery rate and risk factors for early surgery were identified.
Results: Fifteen patients (15.6%) underwent early surgery. The cumulative surgery rate was 8.6% after 6 months, 11.9% after 12 months, 14.1% after 18 months, and 16.7% after 24 to 36 months. Multivariate analysis revealed penetrating or stricturing behavior to be an independent risk factor for early surgery (p<0.001, Exp (B)=2.97 CI 1.39-6.37).
Conclusions: The cumulative early surgery rate in Korean patients seems to be lower than Western patients. Penetrating or stricturing behavior is significantly associated with early surgery, requiring early aggressive medical treatments.
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KEYWORD
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Crohn¡¯s disease, Early surgery, Complications, Stricture
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